Things are looking pretty grim for Wake Forest as the Demon Deacons suffered yet another loss to unranked opposition, this time a 1-0 defeat to College of Charleston. A 61st minute goal by Francis Twohig was enough for Charleston and No. 19 Wake Forest was again held to a shutout, their third of the season. The loss moves the 2007 national champions to 2-3-1 on the year and puts them in serious danger of falling out of the top 25.

Elsewhere, No. 2 Tulsa survived an overtime challenge from Missouri State to win 2-1. An Edin Sabic free kick gave Missouri State a halftime lead but Adrian Klammer netted the equalizer in the 76th minute. Austin Neil sealed the victory in the 107th minute with a close-range rebound. The Golden Hurricanes now focus on their upcoming clash with top-ranked Akron in a rare matchup of the top two teams in the country.

Check out the rest of the early-week action in the NCAA after the jump.

TUESDAY'S COLLEGE SCOREBOARD

No. 10 Boston College 2, Rhode Island 0: Goals from Charlie Rugg and Edvin Worley backed up an Eagles defense that has not given up a goal in three straight matches. 

No. 3 North Carolina 2, Wofford 1 (OT): The Tarheels survived an overtime scare of their own but notched a victory thanks to a Kirk Urso golden goal in the 95th minute.

No. 7 Virginia 2, American University 0: Goals from Will Bates and Brian Ownby were enough for the Cavaliers.

No. 11 Duke 1, UNC-Wilmington 0: Ryan Finley continued his torrid scoring pace with a 21st-minute game winner.

No. 5 Maryland 2, George Mason 0: Maryland got the victory on the 1,000th soccer match in school history with a goal from London Woodberry and an own goal by George Mason. 

WEDNESDAY'S COLLEGE SCOREBOARD

No. 23 Ohio State 0, No. 8 Louisville 0: Neither the Buckeyes nor the Cardinals could capitalize on any of their numerous chances.

No. 15 Michigan State 2, Duquesne 1: Kevin Cope netted a game winner for the Spartans in the 57th minute.