Bobby Wood faces a massive test over the weekend, headlining the contingent of Americans Abroad.
The U.S. Men’s National Team forward takes on Bayern Munich on Saturday as Hamburg looks to pull a major upset on the reigning Bundesliga champions. Any sort of Hamburg result would be a major boost for current leaders Borussia Dortmund, who could see Christian Pulisic feature in a match against Timmy Chandler and Eintracht Frankfurt
In England, DeAndre Yedlin and Newcastle have an opportunity to pick up some points against lowly Crystal Palace while Danny Williams and Huddersfield face an uphill battle against Manchester United.
Elsewhere, Weston McKennie could make his return from injury, Jonathan Gonzalez looks to bounce back from Monterrey’s first defeat midweek and Matt Miazga and Vitesse take on Heerenveen.
Here’s a closer look at this weekend’s Americans Abroad:
Danny Williams and Huddersfield Town face Manchester United on Saturday.
Geoff Cameron and Stoke City face Emerson Hyndman and Bournemouth on Saturday.
Tim Ream and Fulham face Aston Villa on Saturday.
Lynden Gooch and Sunderland face Brentford on Saturday.
Eric Lichaj and Nottingham Forest face Burton Albion on Saturday.
Cameron Carter-Vickers and Sheffield United face Reading on Saturday.
Weston McKennie and Schalke face Mainz on Friday.
Fabian Johnson and Borussia Monchengladbach face Bayer Leverkusen on Saturday.
Christian Pulisic and Borussia Dortmund face Timmy Chandler and Eintracht Frankfurt on Saturday.
Bobby Wood and Hamburg face Bayern Munich on Saturday.
Aron Johannsson and Werder Bremen face Cologne on Sunday.
Jonathan Klinsmann and Hertha Berlin face Caleb Stanko and Freiburg on Sunday.
John Brooks and Wolfsburg face Hoffenhein on Sunday.
Alfredo Morales and Ingolstadt face Heidenheimer SB on Friday.
Jerome Kiesewetter and Fortuna Dusseldorf face McKinzie Gaines, Terrence Boyd and Darmstadt on Friday.
Julian Green and Greuther Furth face Union Berlin on Saturday.
William Yarbrough and Club Leon face Morelia on Friday.
Joe Corona, Michael Orozco, Alejandro Guido and Club Tijuana face Atlas on Friday.
Jorge Villafana, Ventura Alvarado and Santos Laguna face Jonathan Bornstein and Queretaro on Saturday.
Jose Torres and Tigres UANL face Rodrigo Lopez and Toluca on Saturday.
Omar Gonzalez and Pachuca face Puebla on Saturday.
Jonathan Gonzalez and Monterrey face Pumas on Sunday.
Shaq Moore and Levante face Getafe on Saturday.
Shane O’Neill, Desevio Payne and Excelsior face Sparta Rotterdam on Saturday.
Matt Miazga and Vitesse face Heerenveen on Sunday.
Kenny Saeif and Gent face KV Kotrijk on Saturday.
Juan Pablo Torres and KSC Lokoren face Charleroi on Saturday.
Ethan Horvath and Club Brugge face Antwerp on Sunday.
Rubio Rubin and Stabaek face Tromso on Sunday.
Romain Gall and Sundsvall face IFK Norrkoping on Sunday
Mix Diskerud and IFK Goteborg face Ostersunds FC on Sunday.